Guides can be helpful like this, and it's a good start to what's needed. Personally I think any guides like this should be fully incorporated into the game, as opposed to PDFs which you open alongside. It creates a more immersive experience for the player and keeps them within MD, rather than leaving the game and looking at other things.
Feedback on the guide is below, besides other comments above.
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Seems a bit duplicitous having a "Resources Needed" page, and then a "Things You Will Need" page, can these be condensed together?
Repeats what each of the Grasan's produces on page 3 and 5 - one can assume that they'll be able to look back through, so maybe again condense?
Page 9 provides a list of what items you have at this point, and whilst it states "Resources" it may still confuse a new player that you also have Wine, might be best to include this on the list, clarifying that you have it, but don't need it for the process (assuming this doesn't get changed completely based on the fact that there's now other ways to collect Garbage).
Page 12, using the Fenth - third bullet should read "You will be prompted..."
Structure of the message they receive on the fourth bullet is messy, but I'm not sure if that's how you've written it, or what the system genuinely displays.